Fig 4. UBE4B regulates IKK and canonical NF-κB signaling in HTLV-1-transformed cells.

(A-B) UBE4B was inducibly knocked down in C8166 and MT-2 cells by Dox treatment and immunoblotting was performed using lysates with the indicated antibodies. Canonical NF-κB and IKK activation was examined in panel A and noncanonical NF-κB activation was examined in panel B.