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. 2020 Dec 23;16(12):e1008519. doi: 10.1371/journal.pcbi.1008519

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© 2020 Cess, Finley

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Individual time courses for PI3K inhibition of 0.8 at a cycle duration of 25 days with treatment given for 2 days per cycle. Tumors that survived to the end of simulation are shown in black. Tumors that were eliminated are shown in green. One time course is shown in red for ease of understanding. (A) Cancer cells, (B) M0 macrophages, (C) M1 macrophages, (D) M2 macrophages, (E) T cells, (F) Active T cells, (G) Average IL-4, (H) Maximum IL-4, (I) Average IFN-γ, (J) Maximum IFN-γ.