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. Author manuscript; available in PMC: 2022 Mar 1.

Published in final edited form as: Bipolar Disord. 2020 Jul 21;23(2):152–164. doi: 10.1111/bdi.12954

Figure3: — (a) The axial-oblique slices display regions of decreased functional magnetic resonance (fMRI) activationsduring regulation of emotional responses to fearful faces in the medial orbitofrontal cortex (mOFC)that were associated withhopelessness severity, as measured by Beck Hopelessness Scale (BHS). (b)The axial-oblique slices display regions of decreased functional activations during regulation of emotional responses to fearful facesin the mOFC that were associated with hopelessness due to loss of motivation (BHS subscale), when controlled for group and depressed mood. Viewing threshold: p<.001_uncorrected, cluster size=10 voxels.Color bar represents the range of T values. The right side of the image is the right side of the brain.

Figure3: — (a) The axial-oblique slices display regions of decreased functional magnetic resonance (fMRI) activationsduring regulation of emotional responses to fearful faces in the medial orbitofrontal cortex (mOFC)that were associated withhopelessness severity, as measured by Beck Hopelessness Scale (BHS). (b)The axial-oblique slices display regions of decreased functional activations during regulation of emotional responses to fearful facesin the mOFC that were associated with hopelessness due to loss of motivation (BHS subscale), when controlled for group and depressed mood. Viewing threshold: p<.001_uncorrected, cluster size=10 voxels.Color bar represents the range of T values. The right side of the image is the right side of the brain.