Table 1.
CD39 and CD73 expression on CD8+ T cells from PDAC-bearing mice and healthy animals
| Naïve, % |
Effector, % |
Effector memory, % |
Central memory, % |
||||||
|---|---|---|---|---|---|---|---|---|---|
| CD8 | mean | SD | mean | SD | mean | SD | mean | SD | |
| healthy spleen | CD39 | 5.029 | 2.725 | 14.03 | 7.73 | 55.93 | 16.29 | 23 | 11.15 |
| CD73 | 80.8 | 5.07 | 65.89 | 10.53 | 44.05 | 17.7 | 83.21 | 5.679 | |
| PDAC spleen | CD39 | 8.688** | 3.674 | 25.44*** | 9.885 | 61.34 | 13.94 | 39.27*** | 11.44 |
| CD73 | 84.2* | 3.703 | 68.55 | 9.433 | 42.68 | 13.72 | 88.33** | 2.851 | |
| tumor | CD39 | 20.16 | 6.506 | 85.36 | 8.083 | 88.2 | 6.447 | 58.1 | 11.83 |
| CD73 | 84.2 | 3.703 | 68.55 | 9.433 | 42.68 | 13.72 | 88.33 | 2.851 | |
Abbreviations: PDAC, pancreatic ductal adenocarcinoma
Statistically significant difference between levels in spleens from tumor-bearing and healthy mice (n = 8–27; *P < 0.05, **P < 0.01, ***P < 0.001).