Table 2.
CD39 and CD73 expression on CD4+ T cells from PDAC-bearing mice and healthy animals
| Naïve, % |
Effector, % |
Effector memory, % |
Central memory, % |
||||||
|---|---|---|---|---|---|---|---|---|---|
| CD4 | mean | SD | mean | SD | mean | SD | mean | SD | |
| healthy spleen | CD39 | 9.81 | 3.98 | 44.63 | 10.63 | 77.5 | 3.52 | 62.23 | 6.83 |
| CD73 | 39.87 | 9.56 | 71.62 | 12.21 | 88.65 | 3.36 | 67.7 | 5.94 | |
| PDAC spleen | CD39 | 10.79 | 5.25 | 45.80 | 12.45 | 66.62* | 9.85 | 77.69* | 10.45 |
| CD73 | 46.18 | 4.33 | 73.41 | 13.51 | 82.49** | 3.09 | 63.3 | 12.88 | |
| tumor | CD39 | 32.43 | 16.01 | 77.67 | 12.13 | 82.7 | 6.49 | 78.19 | 8.98 |
| CD73 | 63.03 | 15.3 | 86.62 | 14.26 | 95.59 | 1.43 | 93.76 | 2.41 | |
Abbreviations: PDAC, pancreatic ductal adenocarcinoma
Statistically significant difference between levels in spleens from tumor-bearing and healthy mice (n = 8–27; *P < 0.05, **P < 0.01).