Table 3. Genotypic & allelic frequencies of the studied cohort (cases vs. controls).

			Case (n = 105)	Control (n = 106)	OR (95% CI)	X2	P value
IL-18-607 C/A (rs1946518)	Genotypes	CC	29 (27.6%)	16 (15.1%)	Reference
		AC	63 (60%)	81 (76.4%)	0.43 (0.22–0.88)	5.88	0.015*
		AA	13 (12.4%)	9 (8.5%)	0.8 (0.3–2.3)	0.18	0.671
	Alleles	C	121 (57.6%)	113 (53.3%)	Reference
		A	89 (42.4%)	99 (46.7%)	0.84 (0.57–1.23)	0.8	0.372
	Dominant model	CC	29 (27.6%)	16 (15.1%)	Reference
		AC + AA	76 (72.4%)	90 (84.9%)	0.47 (0.24–0.93)	4.93	0.026*
	Recessive model	AA	13 (12.4%)	9 (8.5%)	Reference
		AC+CC	92 (87.6%)	97 (91.5%)	0.66 (0.28–1.67)	0.85	0.355
IL-18-137 G/C (rs187238)	Genotypes	GG	56 (53.3%)	41 (38.7%)	Reference
		GC	40 (38.1%)	23 (21.7%)	1.27 (0.66–2.39)	0.53	0.467
		CC	9 (8.6%)	42 (39.6%)	0.16 (0.07–0.37)	21.81	<0.001*
	Alleles	G	152 (72.4%)	105 (49.5%)	Reference
		C	58 (27.6%)	107 (50.5%)	0.37 (0.25–0.56)	23.14	<0.001*
	Dominant model	GG	56 (53.3%)	41 (38.7%)	Reference
		GC+CC	49 (46.7%)	65 (61.3%)	0.55 (0.32–0.95)	4.56	0.033*
	Recessive model	CC	9 (8.6%)	42 (39.6%)	Reference
		GC+GG	96 (91.4%)	64 (60.4%)	7 (3.27–15.58)	27.75	<0.001*
IFN-γ+874 T/A (rs2430561)	Genotypes	TT	16 (15.2%)	8 (7.5%)	Reference
		AT	60 (57.1%)	49 (46.2%)	0.61 (0.25–1.57)	1.09	0.298
		AA	29 (27.6%)	49 (46.2%)	0.3 (0.11–0.74)	6.47	0.011*
	Alleles	T	118 (56.2%)	147 (69.3%)	Reference
		A	92 (43.8%)	65 (30.7%)	1.76 (1.19–2.63)	7.81	0.005*
	Dominant model	TT	29 (27.6%)	49 (46.2%)	Reference
		AT+AA	76 (72.4%)	57 (53.8%)	2.25 (1.58–4.01)	7.84	0.005*
	Recessive model	AA	16 (15.2%)	8 (7.5%)	Reference
		AT+TT	89 (84.8%)	98 (92.5%)	0.45 (0.19–1.09)	3.1	0.079