. 2021 Jan 7;16(1):e0245302. doi: 10.1371/journal.pone.0245302

Table 2. Comparison of liver mRNA expression in WT mice with and without cholesterol-supplementation.

Mouse populations	LDLR	HMG-CoAR	ACAT2	CYP7A1
WT with cholesterol supplementation	1.0 (0.3)^b	5.3 (1.0)^a	22.7 (3.7)^b	11.8 (6.1)^a
WT without supplementation	2.5 (0.5)	11.7 (3.7)	7.8 (0.8)	2.0 (1.5)

^ap < 0.05

^bp < 0.005; unpaired Student t test. ACAT2: acyl CoA:cholesterol acyl transferase 2; CYP7A1: cytochrome P450 7A1; HMG-CoAR: 3-hydroxy-3-methylglutaryl-CoA reductase; LDLR: LDL receptor; WT: wild type mice.