Table 4. Serological responses to 60-day and 30-day nifurtimox (NFX) treatment assessed 12 months after the end of treatment by indirect haemagglutination testing (full analysis set).
| Baseline | 12 months after the end of treatment | |||||
|---|---|---|---|---|---|---|
| NFX 60 d (n = 219) | NFX 30 d (n = 111) | Total (N = 330) | NFX 60 d (n = 219) | NFX 30 d (n = 111) | Total (N = 330) | |
| Response, n (%) | ||||||
| Reactive | 216 (98.6) | 111 (100) | 327 (99.1) | 199 (90.9) | 103 (92.8) | 302 (91.5) |
| Non-reactive | 2 (0.9) | 0 | 2 (0.6) | 11 (5.0) | 5 (4.5) | 16 (4.8) |
| Missing | 1 (0.5) | 0 | 1 (0.3) | 9 (4.1) | 3 (2.7) | 12 (3.6) |
| Titre* | ||||||
| Mean (SD) | 10.3 (2.11) | 10.6 (1.99) | 10.4 (2.07) | 9.5 (2.35) | 9.8 (2.33) | 9.6 (2.35) |
| Median (range) | 11 (4–12) | 12 (5–12) | 11 (4–12) | 10 (4–12) | 11 (4–12) | 10 (4–12) |
d, days; SD, standard deviation.
*Titres are given as–log2 transformed values.