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Ophiopogonin D increases SERCA2a interaction with phospholamban by promoting CYP2J3 upregulation (abbreviation: LCCs: L-type calcium channel; EETs: epoxyeicosatrienoic acids; DHPR: dihydropyridine receptor; RyRs: ryanodine receptor; SERCA2a: Ca2 + -ATPase2a; PLB: phospholamban; ER: endoplasmic) reticulum.
