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. 2020 Dec 31;2020:8857906. doi: 10.1155/2020/8857906

Figure 6.

Figure 6

Effects of OPD on ER Ca2+ uptake and Ca2+-ATPase activity in HF cells. (a) Effects of OPD on the Ca2+-ATPase activity measured by the quantity of Pi. The activity of SERCA2a was decreased in the ISO-treatment group, ##P < 0.01 versus the control group; OPD (1 μmol/L) induced the Ca2+-ATPase activity, ∗∗∗P < 0.005 versus the ISO-treatment group. (b, c) Effects of OPD followed ISO (1 μM) on [Ca2+]SR. Application of 1 μM ISO indicated complete depletion of [Ca2+] in the SR compared with the control group, ###P < 0.005. Twenty-four hour application of OPD increased the Ca2+ uptake in ER, ∗∗∗P < 0.005 versus the ISO-treated group, n = 3 per group.