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. 2020 Dec 31;2020:6694214. doi: 10.1155/2020/6694214

Figure 2.

Figure 2

Bergenin inhibits the formation of the extracellular matrix. (a) Levels of serum HA and LN expressed as the mean ± SD (n = 8). (b) mRNA expression of collagen I, α-SMA, and TIMP1 assessed by real-time PCR (n = 8). (c) Protein expression of collagen I, α-SMA, and TIMP1 assessed by western blotting. The quantitative evaluation was determined by relative band density. (d) Immunohistochemical staining of α-SMA and TIMP1 (original magnification = 200x). ∗p < 0.05 for CCl4/BDL vs. sham, #p < 0.05 for CCl4/BDL+B20 vs. CCl4/BDL, and ^p < 0.05 for CCl4/BDL+B40 vs. CCl4/BDL+B20.