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. Author manuscript; available in PMC: 2021 Jan 7.
Published in final edited form as: FASEB J. 2020 Jun 15;34(8):10073–10095. doi: 10.1096/fj.202000672R

Fig. 1: Effect of NK1 receptor antagonist and agonists on Ca2+ transients in ICC-IM.

Fig. 1:

A STMs showing the effect of the NK1 receptor antagonist RP 67580 (1 μM) on Ca2+ transients in ICC-IM. B Summary data of the effects of RP 67580 on Ca2+ transient frequency, amplitude, duration and spatial spread, c=14, n=5. C STMs showing the effects of NK1 receptor agonist, Substance P (1 μM), on Ca2+ transients in ICC-IM in the presence of tetrodotoxin (TTX, 1 μM). D Summary data of the effect of Substance P on Ca2+ transient frequency, amplitude, duration and spatial spread, c=13, n=5. E STMs showing the effects of the NK1 receptor agonist, GR 73632 (1 μM), on Ca2+ transients in ICC-IM in the presence of TTX (1 μM). F Summary data of the effects of GR 73632 on Ca2+ transient frequency, amplitude, duration and spatial spread, c=11, n=4.