A Image of two adjacent ICC-IM in the CM layer of the proximal colon of a Kit-Cre-GCaMP6f mouse. Cells are highlighted by Blue (Cell 1) or Red (Cell 2) boxes. B Plot profiles of the summated Ca2+ transient activating in the two-highlighted ICC-IM in A, Period of excitatory EFS (10Hz, 10 sec, L-NNA (100 μM) + MRS 2500 (1 μM)) is shown by the dashed black box. C STMs of the Ca2+ transient activity in Cell 1 and Cell 2 in A. Period of excitatory EFS (10Hz, 10 sec, L-NNA (100 μM) + MRS 2500 (1 μM)) is shown by the dashed white boxes.