A STM of Ca2+ transients in ICC-IM showing the effects of excitatory EFS (10Hz, 10 sec, L-NNA (100 μM) + MRS 2500 (1 μM)) before and after application of AF-DX 116 (0.1 μM) and DAU 5884 (0.1 μM) B Summarized effects of AF-DX 116 and DAU 5884 on Ca2+ transient frequency, amplitude, duration and spread during EFS in the presence of L-NNA and MRS 2500 (c=16, n=6).