Table 1. Changes in the levels of MMP-2 and TIMP-1 in rabbit corneal stroma after CXL.
| Variables | Day 0 | Day 3 | Day 7 | Day 15 | Day 30 | Day 90 | Day 180 | χ2 | P |
| MMP-2 | 0.76±0.07 | 2.78±1.39a | 4.12±0.69a | 2.00±0.29a | 2.00±0.30a | 1.22±0.18 | 1.35±0.18 | 33.14 | 0.000 |
| TIMP-1 | 1.83±0.26 | 7.94±0.58a | 6.95±2.64a | 3.81±0.48a | 3.07±0.92 | 1.72±0.19 | 1.69±0.74 | 31.36 | 0.000 |
| MMP-2/TIMP-1 | 0.42±0.33 | 0.36±0.20 | 0.62±0.10 | 0.54±0.15 | 0.68±0.13a | 0.71±0.10a | 0.68±0.09a | 17.29 | 0.008 |
MMP: Matrix metalloproteinase; TIMP: Tissue inhibitors of matrix metalloproteinase; CXL: Corneal cross-linking; Day 0: Before CXL. aP<0.05 vs baseline.
10−9 mol/g