Table 2. Paired comparison of MMP-2 and TIMP-1 content in rabbit corneal stroma at different time points after CXL.
Variables | Day 0-3 | Day 0-7 | Day 0-15 | Day 0-30 | Day 0-90 | Day 0-180 | Day 3-7 | Day 3-30 | Day 3-90 | Day 3-180 | Day 7-90 | Day 7-180 | Day 30-90 |
MMP-2 | 0.001 | 0.000 | 0.001 | 0.002 | b | b | b | b | 0.016 | b | 0.000 | 0.001 | 0.033 |
TIMP-1 | 0.000 | 0.001 | 0.033 | b | b | b | b | 0.023 | 0.000 | 0.001 | 0.000 | 0.005 | b |
MMP-2/TIMP-1 | b | b | b | 0.011 | 0.008 | 0.023 | 0.033 | 0.005 | 0.003 | 0.011 | b | b | b |
MMP: Matrix metalloproteinase; TIMP: Tissue inhibitors of matrix metalloproteinase; CXL: Corneal cross-linking; Day 0: Before CXL. bP>0.05. Statistical results of paired comparison with P>0.05 were not listed in the table.
P values