Table 3. Medical therapy and surgical intervention.
Patient | Eye affected | Systemic antifungal therapy and duration | Intravitreal antifungal therapy | No. of intravitreal injections |
Surgical intervention | Oral steroids | Intravitreal steroids | |
RE | LE | |||||||
1 | LE | Fluconazole, 3wk | Voriconazole (100 µg/0.1 mL) | 1 | Lensectomy, vitrectomy with secondary IOL implantation | - | - | |
2 | RE | Fluconazole, 2wk | Voriconazole (100 µg/0.1 mL) | 1 | Diagnostic vitrectomy initially, later combined phacoemulsification, IOL implantation, gas tamponde with endolaser and subsequently vitrectomy with silicone oil tamponade | - | - | |
3 | Both | Voriconazole, 48wk | Voriconazole (50 µg/0.1 mL) | 3 | 1 | Vitrectomy in each eye | +48wk | - |
4 | Both | Fluconazole, 22wk | Voriconazole (100 µg/0.1 mL) | 4 | 4 | Vitrectomy in each eye | +36wk | +one injection of dexamethasone (0.4 mg/0.1 mL) in each eye |
5 | LE | Voriconazole, 40wk | Voriconazole (50 µg/0.1 mL) | 8 | Vitrectomy twice at 16 week-interval because of non-clearing vitritis | +40wk | +one injection of dexamethasone (0.4 mg/0.1 mL) | |
6 | RE | Fluconazole, 6wk | Voriconazole (100 µg/0.1 mL) | 1 | Vitrectomy | - | - | |
7 | RE | Fluconazole, 2wk | Did not receive | 0 | Vitrectomy | - | - | |
8 | Both | Fluconazole, 8wk | Amphotericin (5 µg/0.1 mL) | 1 | 1 | RE lensectomy and vitrectomy, no surgical intervention in LE | - | - |
9 | Both | Fluconazole, 6wk | Amphotericin (5 µg/0.1 mL) | 1 | 0 | RE vitrectomy, no surgical intervention in LE | - | - |
10 | Both | Fluconazole, 6wk initially and for 5 additional months on LE recurrence | LE amphotericin on recurrence of EFE (5 µg/0.1 mL) | 0 | 1 | No surgical intervention in either eye | - | - |
11 | Both | Fluconazole, 8wk | RE voriconazole, (100 µg/0.1 mL) LE amphotericin (one injection; 5 µg/0.1 mL), then voriconazole (one injection) | 3 | 2 | Vitrectomy in each eye | +8wk | - |
12 | Both | Amphotericin, 8wk | Voriconazole (100 µg/0.1 mL) | 2 | 1 | Vitrectomy in each eye | - | - |
13 | RE | Voriconazole, 5wk | Two injections of amphotericin (10 µg/0.1 mL), later one injection of voriconazole (100 µg/0.1 mL) | 3 | Vitrectomy | +5wk | - |
RE: Right eye; LE: Left eye; IOL: Intraocular lens.