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. 2020 Nov 24;39(1):81–97. doi: 10.1007/s40273-020-00986-4

Table 4.

Productivity loss analysis by cost elements used

Cost elements used
Absenteeism only Presenteeism only Absenteeism + presenteeism Absenteeism + others Unemployment/early retirement Premature mortality Other, not specifiedb
Totala (N = 208) 98 (47%) 1 (0%) 29 (14%) 32 (15%) 21 (10%) 22 (11%) 39 (19%)
Cost elements used by disease area
 Cardiovascular and metabolic (n = 33) 25 (76%) 0 (0%) 0 (0%) 2 (6%) 0 (0%) 3 (9%) 4 (12%)
 Immunology (n = 55) 22 (40%) 1 (2%) 11 (20%) 12 (22%) 15 (27%) 3 (5%) 11 (20%)
 Central nervous system/psychiatry (n = 42) 23 (55%) 0 (0%) 8 (19%) 4 (10%) 4 (10%) 1 (2%) 7 (17%)
 Oncology (n = 25) 8 (32%) 0 (0%) 0 (0%) 7 (28%) 1 (4%) 9 (36%) 8 (32%)
 Respiratory/Infectious (n = 27) 14 (52%) 0 (0%) 5 (19%) 3 (11%) 1 (4%) 3 (11%) 4 (15%)
 Others (n = 26) 6 (23%) 0 (0%) 6 (23%) 4 (15%) 0 (0%) 3 (12%) 12 (46%)
Cost elements used by region
 North America (n = 51) 21 (41%) 0 (0%) 7 (14%) 9 (18%) 3 (6%) 7 (14%) 12 (24%)
 Europe and Central Asia (n = 109) 50 (46%) 1 (1%) 17 (16%) 18 (17%) 12 (11%) 11 (10%) 19 (17%)
 Latin America and Caribbean (n = 13) 8 (62%) 0 (0%) 2 (15%) 1 (8%) 3 (23%) 2 (15%) 0 (0%)
 Middle East and North Africa (n = 6) 3 (50%) 0 (0%) 1 (17%) 2 (33%) 1 (17%) 0 (0%) 0 (0%)
 South Asia, East Asia and Pacific (n = 25) 14 (56%) 0 (0%) 0 (0%) 2 (8%) 1 (4%) 2 (8%) 6 (24%)
 Sub-Saharan Africa (n = 2) 2 (100%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
 Not reported (n = 2) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 2 (100%)
Cost elements used by country income group
 High income (n = 165) 75 (45%) 1 (1%) 25 (15%) 27 (16%) 15 (9%) 18 (11%) 32 (19%)
 Upper-middle income (n = 32) 16 (50%) 0 (0%) 4 (13%) 3 (9%) 4 (13%) 4 (13%) 5 (16%)
 Lower-middle income (n = 9) 7 (78%) 0 (0%) 0 (0%) 2 (22%) 1 (11%) 0 (0%) 0 (0%)
 Not reported (n = 2) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 2 (100%)
Cost elements used by period of evaluation
 2010.1 to 2012.12 (n = 66) 31 (47%) 1 (2%) 5 (8%) 8 (12%) 7 (11%) 8 (12%) 15 (23%)
 2013.1 to 2014.12 (n = 40) 17 (43%) 0 (0%) 5 (13%) 8 (20%) 4 (10%) 6 (15%) 10 (25%)
 2015.1 to 2016.12 (n = 44) 22 (50%) 0 (0%) 8 (18%) 9 (20%) 4 (9%) 4 (9%) 5 (11%)
 2017.1 to 2018.12 (n = 40) 18 (45%) 0 (0%) 8 (20%) 5 (13%) 3 (8%) 3 (8%) 7 (18%)
 2019.1 to 2019.10 (n = 18) 10 (56%) 0 (0%) 3 (17%) 2 (11%) 0 (0%) 1 (6%) 2 (11%)
Cost elements used by time horizon
 Less than 1 year (n = 24) 16 (67%) 0 (0%) 3 (13%) 1 (4%) 1 (4%) 2 (8%) 2 (8%)
 1–10 years (n = 78) 39 (50%) 0 (0%) 11 (14%) 11 (14%) 7 (9%) 5 (6%) 15 (19%)
 More than 10 years (n = 34) 10 (29%) 0 (0%) 9 (26%) 6 (18%) 6 (18%) 5 (15%) 6 (18%)
 Lifetime (n = 55) 25 (45%) 1 (2%) 4 (7%) 13 (24%) 5 (9%) 8 (15%) 11 (20%)
 Not available (n = 17) 8 (47%) 0 (0%) 2 (12%) 1 (6%) 2 (12%) 2 (12%) 5 (29%)

aGrand total is higher than the number of studies as some studies included more than one productivity cost element

bThirty-one studies simply state that productivity loss was incorporated in modeling without explicitly specifying the exact elements