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. 2021 Jan 5;12(1):44. doi: 10.1038/s41419-020-03322-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A H&E, Masson trichrome, and Sirius red staining of sham, UUO at 3, 6, and 10 days. Scale bar = 100 μm. B Quantitative tubular injury scores of different groups assessed according to H&E staining. C Quantification of Masson trichrome and Sirius staining in different groups. D Immunohistochemistry staining of α-SMA, p53, p21, and Ki-67 in different groups and E their quantifications. Scale bar = 100 μm for α-SMA and scale bar = 50 μm for p53, p21, and Ki-67. **P < 0.01; ***P < 0.001 compared with sham group.