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. 2021 Jan 5;12(1):44. doi: 10.1038/s41419-020-03322-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A Immunohistochemistry staining and enlarged images of F4/80-positive macrophages in the interstitium of sham, UUO + vector, UUO + p53 plasmid, and UUO + p53 shRNA group and B their quantifications. Scale bar = 100 μm. C Relative mRNA expression of IL-1β, IL-6, and TNF-α in kidneys from different groups. ***P < 0.001 compared with the sham group. ^#P < 0.05; ^##P < 0.01; ^###P < 0.001 compared with the UUO + vector group.