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. 2021 Jan 7;12(1):22. doi: 10.1038/s41419-020-03272-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A, B Expression of Glut1 and HIF-1α in CD4⁺ Tregs of human ovarian cancer (n = 10) peripheral blood, benign ovarian cancer (n = 10) peripheral blood and healthy control (n = 10) peripheral blood, as detected via flow cytometry. Left images are the representative flow cytometric analysis and plots are gate on CD4⁺CD25⁺CD127⁻. Right bar diagram summarizes the expression ratios as the mean ± SEM; *P < 0.05; **P < 0.01; ***P < 0.001. C, D Left images are the representative flow cytometric analysis of Glut1 and HIF-1α in CD4⁺ Tregs and Teffs of OC (n = 10) and plots are gate on CD4⁺CD25⁺CD127⁻ or CD4⁺CD25⁻CD127⁺. Right bar diagram shows the proportions of Glut1 and HIF-1α in CD4⁺ Tregs and Teffs. Data are displayed as mean ± SEM; *P < 0.05; ****P < 0.0001.