Approach and features of genomics and transcriptomics datasets. (a) Photo- micrograph of skin and detailing the laser capture microdissection approach to isolate epidermal and SCCIS samples. Scale bar = 0.25mm (b) Coverage summary of mapped reads for exome-seq samples; E-epidermal library, T-SCCIS library. (c, d): Summary of the genetic class for exome-seq (c) or RNA-seq (d) samples. ncRNA: non-coding RNAs = rRNA, tRNA, miRNA, snoRNA, etc. repeat: RMSK annotated transposons, tandem-repeats or RNAs. Intergenic: genomic regions without annotation.