Table 2.
Immune cell distribution changes between baseline and 8 weeks of test substance administration
| Cell (%) | KRG group (n = 49) |
Placebo group (n = 50) |
p-value‡ | |||
|---|---|---|---|---|---|---|
| Mean ± SD | p-value∗ | Mean ± SD | p-value† | |||
| Total T cell (CD3) | W0 | 76.86 ± 8.33 | 75.76 ± 6.45 | 0.0348‡ | ||
| W8 | 78.38 ± 10.65 | 0.2178 | 73.81 ± 8.31 | 0.0752 | ||
| W8–W0 | 1.52 ± 8.53 | −1.95 ± 7.57 | ||||
| Helper T cell (CD3+CD4+) | W0 | 48.86 ± 8.73 | 48.05 ± 8.42 | 0.0381‡ | ||
| W8 | 49.95 ± 11.48 | 0.3507 | 45.80 ± 7.71 | 0.0444† | ||
| W8–W0 | 1.09 ± 8.11 | −2.25 ± 7.72 | ||||
| Cytotoxic T cell (CD3+CD8+) | W0 | 25.65 ± 9.04 | 25.72 ± 10.82 | 0.0498‡ | ||
| W8 | 28.64 ± 12.64 | 0.0680 | 23.39 ± 10.88 | 0.2808 | ||
| W8–W0 | 2.93 ± 11.09 | −2.33 ± 15.08 | ||||
| B cell (CD19) | W0 | 7.85 ± 3.63 | 8.03 ± 3.34 | 0.0061‡ | ||
| W8 | 9.92 ± 5.65 | 0.0004∗ | 8.16 ± 2.99 | 0.7605 | ||
| W8–W0 | 2.07 ± 3.79 | 0.13 ± 3.05 | ||||
| WBC ( × 108/μL) | W0 | 4.67 ± 0.88 | 4.96 ± 0.79 | 0.0490‡ | ||
| W8 | 5.10 ± 1.22 | 0.0179∗ | 4.96 ± 0.91 | 0.9635 | ||
| W8–W0 | 0.43 ± 1.23 | 0.01 ± 0.86 | ||||
KRG, Korean Red Ginseng; SD, standard deviation; WBC, white blood cell; W8, 8th week; W0, Baseline.
∗
Analyzed by Paired t-test (compared within treatment group).
†
Analyzed by Paired t-test (compared within control group).
‡
Analyzed by Paired t-test (compared between groups: baseline–8th week).