Fig. 2.

Effects of KRG on BPA-induced NF-κB activation. (A) A549 cells were transfected with the NF-κB luciferase reporter gene. The next day, A549 cells were pretreated with KRG for 1 h and then treated with BPA for 24 h. Luciferase activities of NF-κB were measured. (B) A549 cells were treated as described in (A). The cytoplasmic and nuclear protein extracts were isolated with different lysis buffers. NF-κB p65, lamin B, and β-actin were evaluated by western blot analysis. #p < 0.05 and ##p < 0.01, CON vs. BPA; *p < 0.05, BPA vs. BPA + KRG.

NF-κB, nuclear factor-kappa B; KRG, Korean Red Ginseng; BPA, bisphenol A.