Fig. 4.

Rk1 and Rg5 suppress TGF-β1-induced Snail and Slug, EMT-induced transcription factor. A549 cells were treated with the indicated concentration of Rk1 or Rg5 and stimulated with TGF-β1 (5 ng/mL) for 48 h. A and B. Change in protein expression of Snail and Slug was analyzed by Western blot analysis and densitometric quantification. β-Actin was used as a loading control. ∗∗p < 0.01, ∗p < 0.05 versus control and ##p < 0.01 #p < 0.05 versus TGF-β1 treated control. The data are expressed as mean ± SD for triplicates.