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. 2020 Jan 14;45(1):1–21. doi: 10.1016/j.jgr.2019.12.009

Table 2.

The advantages and shortcomings of technique analysis for Panax species

Technique Advantages Shortcomings Reference
TLC/HPTLC Rapid analysis
Convenient operation
High sensitivity and specificity
Low cost
Bad efficiency in separation
Bad stability
Need volatile organic solvents
Low accuracy in quantification
[[24], [25], [26]]
GC Rapid analysis
Less solvent consuming
High sensitivity
Less time analysis
Limited to volatile compounds
Operation with the derivation
High cost
[76,130]
HPLC/UHPLC UV/DAD Convenient operation
High specificity
High repeatability
Low cost
Combining with multiple detector
Long analysis time
Large solvent consuming
Analytes with ultraviolet absorption
Low sensitivity
[[131], [132], [133]]
ELSD High specificity
Low cost
Long analysis time
Large solvent consuming
Low sensitivity
[52,77,104]
MS Convenient operation
High sensitivity
Less solvent consuming
High resolution
High cost
Bad stability
[93,134,135]
2D-LC Wide coverage
Good orthogonality
High efficiency in separation
Complicated operation
Long analysis time
Large solvent consuming
[55,56]
Ambient ionization mass spectrometry Rapid analysis
Convenient operation
Less solvent consuming
Bad stability
High cost
Low sensitivity
Some compound with the derivation
[59]
HSCCC/HPCCC High efficiency in separation More solvent consuming
Low sensitivity
[62,136]
1H NMR Fast analysis
Less solvent consuming
Easy operation
High cost
Low accuracy in quantification
[65,66]
Near infrared Fast analysis
No solvent consuming
No sample preparation
Low cost
Low accuracy in quantification
Low specificity
[137,138]