Table 2.

Variables associated with the development of suspected hospital-acquired sepsis in critically ill children on unadjusted analysis

Outcome: Sepsis	Odds Ratio (95% CI)	P Value
Stage 2 or 3 AKI	3.85 (2.74–5.41)	<.001
Stage 2 AKI versus Stage 1 or no AKI	3.43 (2.32–5.08)	<.001
Stage 3 AKI versus Stage 1 or no AKI	5.54 (2.94–10.46)	<.001
Age	0.96 (0.94–0.98)	<.001
History of Heart Failure	4.56 (3.03–6.85)	<.001
History of Liver Failure	9.15 (5.43–15.4)	<.001
Mechanical Ventilation	5.76 (4.58–7.24)	<.001
Vasopressor Use	2.85 (2.25–3.61)	<.001
Surgery Prior to ICU Admission	4.60 (3.57–5.92)	<.001
PIM2 score	1.64 (1.53–1.75)	<.001

Abbreviations: AKI, acute kidney injury; CI, confidence interval; ICU, intensive care unit; PIM2, pediatric index of mortality score; OR, odds ratio