Figure 1.

DPP4 Is Largely Increased in the Diabetic Injured Kidney of CRP^tg db/db Mice

(A) IHC of DPP4 and CD32b in the kidney of 20-week-old mice (original magnification ×400). (B–D) Western blot (B) and real-time PCR (C and D) show the induction of renal DPP4 and CD32b in db/db mice is further promoted in the CRP^tg db/db mice at 20 weeks old. Each bar represents the mean ± SEM for groups of six mice or three independent experiments. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 versus db/m mice; ^#p < 0.05 versus db/db mice.