Table 2.

Frequency of 5′ ALR alleles found in the study population

5′ ALR allele	Nondiabetic [n = 114]	Uncomplicated [n = 72]	Microangiopathic [n = 134]
			Retinopathy [n = 109]	Nephropathy [n = 57]	Neuropathy [n = 110]
					Autonomic [n = 60]	Peripheral [n = 102]
Z − 12	0.0 [0]	0.0 [0]	0.4 [1]	0.8 [1]	0.8 [1]	0.4 [1]
Z − 10	0.9 [2]	0.0 [0]	0.8 [2]	2.6 [3]	1.6 [2]	0.4 [1]
Z − 8	1.3 [3]	0.0 [0]	0.8 [2]	0.8 [1]	0.8 [1]	0.9 [2]
Z − 6	1.7 [4]	1.4 [2]	0.8 [2]	0.8 [1]	0.0 [0]	1.4 [3]
Z − 4	16.7 [38]	5.6 [8]	31.6 [68]*	29.8 [53]†	31.6 [3]‡	26.4 [54]
Z − 2	9.6 [49]	22.9 [33]	12.4 [27]	10.5 [12]	18.3 [22]	17.1 [35]
Z	33.3 [76]	40.2 [58]	29.8 [65]	21.9 [25]	25.0 [30]	28.4 [58]
Z + 2	17.6 [40]	20.8 [30]	10.0 [22]	7.9 [9]	5.0 [6]	8.8 [18]
Z + 4	3.1 [7]	3.5 [5]	4.1 [9]	1.7 [2]	6.6 [8]	5.4 [11]
Z + 6	1.3 [3]	2.1 [3]	3.6 [8]	3.5 [4]	4.2 [5]	4.4 [9]
Z + 8	1.3 [3]	1.4 [2]	1.3 [3]	0.0 [0]	1.6 [2]	1.9 [4]
Z + 14	0.44 [1]	1.4 [2]	0.0 [6]	1.7 [2]	2.5 [3]	2.4 [5]
Z + 16	0.9 [2]	0.7 [1]	1.3 [3]	0.8 [1]	1.6 [2]	1.4 [3]

Figures in brackets are number of subjects

*Frequency compared with uncomplicated DM χ² = 5.2, P < 0.001

^†Frequency compared with uncomplicated DM χ² = 6.1, P < 0.001

^‡Frequency compared with uncomplicated DM χ² = 6.4, P = 0.031