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. Author manuscript; available in PMC: 2021 Jan 25.
Published in final edited form as: Int J Pharm. 2020 Nov 26;593:120120. doi: 10.1016/j.ijpharm.2020.120120

Fig. 2. – Tight junction gene expression in the small intestine differed in infant mice and adults.

Fig. 2. –

Gene expression was measured using qRT-PCR on intestinal tissue from 2 week old (black) and 12 week old (blue) mice. Relative mRNA expression of the barrier-forming genes Claudin 3, Occludin, ZO-1, and JAM-A was lower in infantile tissue. Expression of the pore-forming genes Claudins 2 and 5 was higher in infantile tissue only in the proximal small intestine. Relative mRNA expression is expressed as percentage of β actin mean ± SEM (n = 6). One-way ANOVA with Tukey’s multiple comparison test; * P < 0.05, ** P < 0.01, *** P < 0.001.