Table 4.
Linear Regression Model of the Impact of the Presence of Lymphedema on Participants’ HRQL at 18 Months adjusted for Intervention Group, Demographic and Clinical Variables
| Variable | Level | Estimate | Standard Error | P-Value | Overall P-Value |
|---|---|---|---|---|---|
| Lymphedema Intervention Group | LEAP | −0.6161 | 1.1482 | 0.5921 | 0.5921 |
| Education Only (EO) | Reference | ||||
| Immediate reconstructive surgery | Yes | −1.8887 | 1.5627 | 0.2281 | 0.2281 |
| No | Reference | ||||
| Definitive primary surgery | Mastectomy, NOS | 1.1734 | 1.4323 | 0.4135 | 0.4135 |
| Partial mastectomy/lumpectomy/excisional biopsy | Reference | ||||
| Race | African-American | −2.0784 | 1.6039 | 0.1964 | 0.3549 |
| Other | 1.4292 | 2.8702 | 0.6190 | ||
| White | Reference | ||||
| ECOG Performance Status | 1 & 2 | −4.2272 | 2.3780 | 0.0768 | 0.0768 |
| 0 | Reference | ||||
| Number of positive lymph nodes | 1–3 | 0.8704 | 1.5469 | 0.5742 | 0.2989 |
| 4+ | −2.1654 | 2.1082 | 0.3055 | ||
| 0 | Reference | ||||
| Lymphedema | Yes | −2.3175 | 1.3288 | 0.0825 | 0.0825 |
| No | Reference | ||||
| Education | At least some college | 0.6585 | 1.3911 | 0.6364 | 0.4045 |
| Post College work/degree | 2.0368 | 1.5706 | 0.1961 | ||
| HS Grad or less | Reference | ||||
| Chemotherapy | Yes | −1.1679 | 1.3790 | 0.3980 | 0.3980 |
| No | Reference | ||||
| AND/SND Status | Axillary node dissection only | −0.4700 | 1.6435 | 0.7752 | 0.9123 |
| Sentinel node biopsy only | −0.6072 | 1.5351 | 0.6928 | ||
| Both Axillary node dissection and sentinel node biopsy | Reference | ||||
| Age | 1 more year | 0.04319 | 0.05546 | 0.4369 | 0.4369 |
| Baseline FACT-B+4 Total Score | 0.6572 | 0.05971 | <.0001 | <.0001 |