Figure 1.

miR-204-3p Was Decreased in the Brain and Plasma of APP/PS1 Mice

(A) Heatmap diagram showing different expression patterns of miRNAs in the hippocampus of 6-month-old APP/PS1 and wild-type (WT) mice. n = 3. (B) The levels of miR-204-3p in the hippocampus of 4-, 6-, and 9-month-old APP/PS1 mice were examined by qPCR. n = 4–7. (C) The levels of miR-204-3p in the plasma of 6-month-old WT and APP/PS1 mice were detected by qPCR. n = 5. All data are presented as means ± SEM. ∗p < 0.05, ∗∗p < 0.01. ns, no significance.