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. 2021 Jan 7;12(1):43. doi: 10.1038/s41419-020-03295-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Schematic diagram of experimental programme. B Cardiac function was assessed by echocardiography in non-diabetic and diabetic rats. Scale bar: 2 mm. C–E Expression levels of Rev-erbα (C), BMAL1 (D), and C/EBPβ (E) mRNA were measured by qPCR over time after reperfusion. F–J The protein levels of Rev-erbα (G), BMAL1 (H), C/EBPβ (I) and LC3 II/I (J) were detected by western blotting in the myocardial tissues of non-diabetes and diabetes. n = 6 per group. ^*P < 0.05 versus NS within ZT; ^#P < 0.05 versus ZT0 within NS; ^&P < 0.05 versus ZT0 within DS.