Table 2.

Top 20 differentially methylated CpG sites resulting from the comparison between BPD+T patients (N = 49) and BPD-T patients and CTL (N = 91).

CpG site	P value	Q value	B	Chr.	Chr. position	Gene	Gene region
cg15948871	9.09E−10	3.86E−04	10.57	6	31139620	POU5F1	TSS1500^a
cg24915915	6.01E−08	1.15E−02	6.45	2	231799064	GPR55	IGR^a
cg04511534	8.10E−08	1.15E−02	6.16	17	4463371	GGT6	Body^a
cg00253346	1.09E−07	1.16E−02	5.87	22	42324281	TNFRSF13C	TSS1500
cg05478172	3.07E−07	2.61E−02	4.86	12	47628981	FAM113B	Body
cg16465769	7.10E−07	5.03E−02	4.04	6	43266151	SLC22A7	1stExon^a
cg26529771	1.07E−06	6.20E−02	3.64	16	89260650	CDH15	Body
cg10030436	1.17E−06	6.20E−02	3.56	X	48755633	PQBP1	5′UTR^b
cg07823755	1.36E−06	6.44E−02	3.40	2	234668355	UGT1A10	Body
cg07583088	1.73E−06	7.25E−02	3.17	16	1181617		IGR
cg20587394	1.88E−06	7.25E−02	3.09	12	54332209	HOXC13	TSS1500
cg13231322	2.21E−06	7.35E−02	2.94	1	32234411		IGR
cg24786705	2.25E−06	7.35E−02	2.92	5	34500318		IGR^a
cg14153321	2.49E−06	7.49E−02	2.82	22	38246051	EIF3L	Body
cg24073755	2.66E−06	7.49E−02	2.76	1	231955433	DISC2	TSS1500
cg02224755	2.82E−06	7.49E−02	2.70	16	1608969	IFT140	Body
cg14788655	3.41E−06	8.33E−02	2.52	11	40224146	LRRC4C	5′UTR
cg25929552	3.53E−06	8.33E−02	2.48	2	67551782		IGR
cg01619107	3.94E−06	8.57E−02	2.38	12	52515354		IGR
cg10188253	4.22E−06	8.57E−02	2.31	19	43908315	TEX101	5′UTR

Q value indicates FDR corrected p values. B indicates log-odds that the gene is differentially expressed.

Bold letters represent statistically significant results.

^aCpGs in two studies: BPD+T vs. BPD-T & CTL and BPD+T vs. BPD-T.

^bCpGs in two studies: BPD vs. CTL and BPD+T vs. BPD-T & CTL.