Figure 3.
LINC01126 promoted hypoxia‐induced apoptosis, inflammation, suppressed proliferation in hPDLCs. (A) The expression of LINC01126 after transfection with pCDH‐01126, sh‐01126 and the corresponding controls. (B‐D) Cell proliferative ability after overexpression or knockdown of LINC01126 under hypoxia or normoxia. (E) ELISA showing the secretion of inflammatory cytokines including IL‐1β IL‐6, IL‐8 and TNF‐α at hypoxic environment (1% O2) after 24 h treatment was determined by ELISA. (F‐G) Cell apoptosis after overexpression or knockdown of LINC01126 under hypoxia or normoxia. Results are presented as mean ± SD (*P < .05, **P < .01, compared with the control group)