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. 2020 Nov 24;54(1):e12957. doi: 10.1111/cpr.12957

Figure 6.

Figure 6

HIF‐1α promotes hypoxia‐induced apoptosis and suppressed proliferation in hPDLCs. (A, B) The mRNA and protein expression of HIF‐1α after transfection with transfection with sh‐LINC01126, pCDH‐HIF‐1α, sh‐HIF‐1α and the corresponding controls. Histogram shows quantification of the band intensities. (C‐E) Cell proliferative ability after overexpression or knockdown of HIF‐1αunder different O2 concentrations was determined by MTT assay. (F) Cell apoptosis ratio after overexpression or knockdown of HIF‐1α under different O2 concentrations. (G‐H) The expression of HIF‐1α mRNA after knockdown of LINC01126 under hypoxia (1% O2, 5% O2). Results are presented as mean ± SD (*P < .05, **P < .01, compared with the control group)