Table 5.
Multivariate analysis of GSDMD expression and osteosarcoma patient survival
| Characteristic | Comparison | Progression-free survival (months) | Overall survival (months) | ||||
|---|---|---|---|---|---|---|---|
|
|
|
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| HR | 95% CI | P-value | HR | 95% CI | P-value | ||
| GSDMD | high expression vs. low expression | 6.43 | 1.60-25.77 | 0.009 | 7.44 | 1.97-28.17 | 0.003 |
| Response to chemotherapy | Good vs. poor | 0.31 | 0.08-1.14 | 0.079 | 0.47 | 0.13-1.69 | 0.249 |
| Distant metastasis | Yes vs. no | 3.36 | 1.08-10.43 | 0.036 | 4.13 | 1.19-14.36 | 0.026 |
HR: hazard ratio; CI: confidence interval; NS: no significance.