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. Author manuscript; available in PMC: 2021 Jan 8.
Published in final edited form as: J Am Board Fam Med. 2020 Nov-Dec;33(6):969–977. doi: 10.3122/jabfm.2020.06.200210

Table 2:

Change in Likelihood of Requesting Antibiotics for URI-Like Symptoms After Reading Each Statement About Potential Harm of Non-Indicated Antibiotics

Statement Delta
Mean
Likelihood
(Standard
Deviation)
Median
(Interquartile
range)
Statement
Category
Discusses
Antibiotic
Resistance?
"Taking antibiotics can hurt your body's natural defenses. This makes it easier for you to get another infection"[1] [9]. −2.56 (2.14) −3 (−5 to −1) Individual No
"Antibiotics can change how babies grow inside pregnant women" [10] [11] −2.54 (2.28) −3 (−5 to 0) Others close to you No
"By changing your normal gut bacteria, antibiotics can cause allergies, asthma, and stomach problems" [10] [12] [13]. −2.54 (2.21) −3 (−5 to −1) Individual No
"Antibiotics can make you more likely to be obese (fat)" [14] −2.51 (2.28) −3 (−5 to 0) Individual No
"Pregnant women who take antibiotics are more likely to have babies with asthma" [11]. −2.50 (2.33) −3 (−5 to 0) Others close to you No
"Antibiotics can cause bad bacteria to overgrow in your gut. This can cause diarrhea and belly pain" [15] [12]. −2.47 (2.17) −3 (−5 to −1) Individual No
"In the future, antibiotic resistance will cause more deaths than cancer and diabetes combined” [6] −2.42 (2.23) −3 (−5 to 0) Society Yes
"Resistant bacteria can still be found in your gut four years after taking antibiotics" [16] −2.30 (2.25) −3 (−4 to 0) Individual Yes
"A single dose of antibiotics makes the bacteria in your body more resistant to treatment" [17] −2.12 (2.26) −2 (−4 to 0) Individual Yes
"Antibiotics kill your normal gut bacteria. This can cause bad bacteria to overgrow" [14] −1.99 (2.35) −2 (−4 to 0) Individual No
"Antibiotic resistant bacteria cause over two million illnesses and twenty-three thousand deaths in the U.S. each year" [9] −1.96 (2.45) −2 (−4 to 0) Society Yes
"Each antibiotic resistant infection costs up to $30,000 more to treat than other infections" [18] [19] [6]. −1.93 (2.30) −2 (−4 to 0) Society Yes
"Taking antibiotics can cause you to get a yeast infection" [20]. −1.90 (2.46) −2 (−4 to 0) Individual No
"Resistant bacteria can spread between people" [1] [9]. −1.85 (2.66) −2 (−4 to 0) Others close to you Yes
"Antibiotics are the most common cause of Emergency Room visits for drug reactions in children" [9]. −1.83 (2.33) −2 (−4 to 0) Others close to you No
"One in five people who take an antibiotic in a hospital will have a side effect" [1]. −1.72 (2.25) −2 (−4 to 0) Society No
"In some countries like India, people in hospitals have infections so resistant that antibiotics can't treat them" [21] −1.40 (2.60) −1 (−4 to 0) Society Yes
"Antibiotic resistance costs the U.S. between $20-35 billion each year" [18] [9]. −1.35 (2.28) −1 (−3 to 0) Society Yes

For the mean delta displayed, a “−5” meant the statement made the patient much less likely to request antibiotics, “0” meant the statement did not change their likelihood, and “5” would mean the statement made them much more likely to request antibiotics.