Table 4.

Mulitivariate Cox Regression Analysis of Clinicopathological Characteristics According to OS and DFS.

	OS		DFS
	Hazard ratio	p value (Wald)	Hazard ratio	p value (Wald)
Tumor budding (High vs Low)	20.899	<0.001	12.7	<0.001
Histological grade (G1 vs G2 or G3)	0.234	0.239	0.352	0.371
LVI (present vs absent)	0.332	0.022	0.275	0.006
Perineural invasion (Yes vs No)	1.398	0.496	1.173	0.750
pTNM (III vs I or II)	0.456	0.112	0.381	0.049