Table 4.

Multivariable COX Analysis of Factors Associated With Death From Different Cause of Death in Elderly Cohort.

Variables	Lung cancer*		Heart disease**		COPD***
	HR (95%CI)	p-value	HR (95%CI)	p-value	HR (95%CI)	p-value
Age		<0.001		<0.001		0.001
70-79
>79	1.28(1.17 -1.40)	<0.001	1.81(1.56-2.09)	<0.001	1.38(1.15 -1.66)	0.001
Surgery		<0.001		0.065		<0.001
Wedge resection	Ref.		Ref.		Ref.
Lobectomy resection	0.75(0.68-0.82)	<0.001	0.85(0.72 -1.01)	0.065	0.45(0.38-0.54)	<0.001
Race				0.001		0.001
White			Ref.		Ref.
Black			0.89(0.63 -1.24)	0.61	0.61(0.39-0.95)	0.030
Others			0.50(0.35-0.72)	<0.001	0.46(0.29-0.74)	0.001
Gender		<0.001		<0.001		<0.001
Male	Ref.		Ref.		Ref.
Female	0.75(0.69-0.81)	<0.001	0.54(0.46-0.62)	<0.001	0.63(0.53-0.76)	<0.001
Tumor grade		<0.001		0.004		<0.001
I	Ref.		Ref.		Ref.
II	2.05(1.80-2.35)	<0.001	1.19(0.97 -1.46)	0.092	1.66(1.27-2.19)	<0.001
III	2.72(2.36-3.14)	<0.001	1.40(1.12 -1.75)	0.003	2.08(1.56-2.78)	<0.001
IV	2.85(2.12-3.85)	<0.001	2.08(1.27-3.40)	0.004	2.09(1.12-3.93)	0.022
Pathological subtypes		0.003		<0.001		<0.001
Adenocarcinoma	Ref.		Ref.		Ref.
Squamous cell carcinoma	1.09(1.00 -1.20)	0.061	1.60(1.37 -1.88)	<0.001	1.76(1.46-2.12)	<0.001
Others NSCLC	1.28(1.10 -1.49)	0.001	1.14(0.85 -1.53)	0.369	1.27(0.91 -1.77)	0.156
Marital status						<0.001
Married					Ref.
Single (never married)					1.21(0.86 -1.71)	0.280
Windowed					1.64(1.34-2.01)	<0.001
Separated/Divorced					1.47(1.11 -1.94)	0.008

*: based on variable including gender, grade, age, surgery and pathological subtypes.

**: based on variable including gender, race, grade, age, surgery and pathological subtypes.

***: based on variable including gender, race, grade, age, surgery, pathological subtypes and marital status.