Table 1.
Existing Data in Support of Non-Operative Management of Rectal Cancer.
| Author (Reference) | Year Published | N | Median Follow-up (months) | LR (%) | DR (%) | DFS (%) | OS (%) |
|---|---|---|---|---|---|---|---|
| Habr-Gama (26) | 2004 | 71 | 57.3 | 2.8 | 4.2 | 92# | 100# |
| Maas (28) | 2011 | 21 | 25 | 4.7 | 0 | 89* | 100* |
| Dalton (31) | 2012 | 6 | 25.5 | 0 | 0 | 100* | 100* |
| Smith (34) | 2012 | 32 | 28 | 18.7 | 9.4 | 88* | 96* |
| Li (33) | 2015 | 30 | 59 | 6.7 | 3.3 | 90# | 100# |
| Smith (32) | 2015 | 18 | 68.4 | 5.6 | 5.6 | NR | NR |
| Araujo (35) | 2015 | 42 | 47.7 | 11.9 | 9.5 | 60.9# | 71.6# |
| Lai (30) | 2016 | 18 | 49.9 | 11.1 | 0 | NR | 100# |
| van der Valk (36) | 2018 | 880 | 39 | 25.2 | 8 | NR | 84.7# |
| Smith (27) | 2019 | 113 | 43 | 19.5 | 8 | 75# | 73# |
| Garcia-Aguilar (8)^ | 2020 | 324 | 25 | NR | NR | NR | NR |
Abbreviations: N, number of patients; LR, local recurrence, DR, distant recurrence; DFS, disease-free survival, OS, overall survival; NR, not reported.
*: Reported at 2 years.
#: Reported at 5 years.
^: Final results of this trial are not available. Current data was reported for the cohort overall, not for patients undergoing organ preservation and was thus omitted from the above table.