Figure 4.

Multitude of factors secreted in the circulatory system with the sustained growth of tumor. A liquid biopsy contains wealth of information relevant to determining tumor status, metastatic potential, and likelihood of relapse. Some of the contributing factors to making such an assessment include circulating tumor cell (CTC) counts, CTC genetic profile and protein expression, levels of circulating tumor DNA/RNA, and the presence or absence of known mutations or epigenetic signatures. A thorough analysis of liquid biopsies from patients with cancer screening for these factors can reveal essential information for personalized care.