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. 2020 Dec 15;12(12):8162–8174.

Figure 1.

Figure 1

Markedly elevated SOX12 in human breast cancer tissues. A. Real-time PCR results of SOX12 mRNA levels in paired breast cancer tissues and adjacent normal tissues (ANTs) (n = 142). B. Relative expression of SOX12 mRNA in breast cancer cases with metastasis (n = 35) and without metastasis (n = 107). C. Relative expression of SOX12 mRNA in breast cancer cases with recurrence (n = 46) and without recurrence (n = 96). D. Relative expression of SOX12 mRNA expression in paired tissues from primary breast cancer and metastatic lesions (n = 32). E. Proportion of breast cancer tissues with positive SOX12 expression being higher than that of ANTs (P < 0.001). F. Higher median immunoreactive score (IRS) of breast cancer tissues than that of ANTs (P < 0.001). G. Representative immunohistochemistry (IHC) images of different SOX12 staining intensities in breast cancer tissues (Scale bar, 50 µm). H. Higher median IRS in estrogen receptor (ER)-positive breast cancer tissues than in ER-negative cases (P = 0.030).