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. 2020 Oct 9;41(12):1671–1681. doi: 10.1093/carcin/bgaa105

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — All possible dichotomized cutoffs for CD3, CD4, CD8, CD20 and CD45RO plotted against P-values indicating significance of DSS for all patient (A) and in the LUSC and LUAD histological subgroups (B and C). Vertical lines and numbers printed on the plot represents median and optimal cutoff values for each marker, respectively. For ease of interpretation, curves are slightly smoothened whenever possible (small dots represent the actual data points). DS, digital score; SQ, semi-quantitative.