Table 4.

The osteoporosis incidence and risk in keloids patients with comorbidity

Variables	Patients with keloids			Patients without keloids			Compared with non-keloids controls
	Osteoporosis	PY	Rate	Osteoporosis	PY	Rate	Adjusted HR(95% CI)a
Hyperlipidemia
No	60	38,378.15	1.56	251	451,138.90	0.57	2.48 (1.85–3.33)*
Yes	118	10,659.27	11.07	336	60,212.42	5.58	2.74 (2.20–3.42)*
Stroke
No	143	47,551.35	3.01	501	504,095.08	0.99	2.59 (2.13–3.16)*
Yes	35	1486.07	23.55	86	7256.23	11.85	2.90 (1.95–4.33)*
Chronic liver disease
No	81	35,472.65	2.28	338	439,113.30	0.77	2.34 (1.82–3.01)*
Yes	97	13,564.77	7.15	249	72,238.01	3.45	2.99 (2.34–3.81)*
Depression
No	125	42,773.81	2.92	467	478,243.51	0.98	2.45 (1.98–3.02)*
Yes	53	6263.61	8.46	120	33,107.81	3.62	3.30 (2.37–4.61)*

PYs Person-year; Rate, incidence rate in per 1000 person-years; 95% CI 95% Confidence interval; HR Hazard ratio

^a Model adjusted for age, gender, Charlson Comorbidity Index and relevant comorbidities

^* P< 0.001