Table 4.

Unadjusted and adjusted odds ratios for the association between baseline pulmonary symptoms as measured by the COPD Assessment Test (CAT) score and pulmonary obstruction or restriction as compared to normal lung function at baseline

	Baseline obstruction				Baseline Restriction
	Unadjusted OR	95% CI	Adjusted ORa	95% CI	Unadjusted OR	95% CI	Adjusted ORa	95% CI
CAT score	0.99	0.53–1.84	0.88	0.45–1.72	1.77	1.18–2.68	1.79	1.15–2.80
Age	1.62	0.81–3.24			0.84	0.51–1.41
Female Gender	0.26	0.05–1.27			1.42	0.60–3.37
CD4 baseline	1.09	0.61–1.92			1.38	0.92–2.08
Log viral load baseline	2.34	0.76–7.15			0.77	0.42–1.42
HbA1c	1.83	0.96–3.49			1.43	0.94–2.16
Sputum TTP	1.38	0.53–3.63			0.78	0.43–1.49
Smoking (current)	2.60	0.53–12.94			1.08	0.32–3.67
Smoking (ever)	3.90	0.94–16.15			1.37	0.45–4.13

Age categorized into < 30, 30–39, 40–49, ≥ 50; Baseline CD4 categorized into < 50, 50–99, 100–199, ≥ 200; HbA1c categorized into < 5.7, 5.7–5.9, 6.0–6.2, ≥ 6.3; CAT score categorized into < 5, 5–9, 10–14, ≥ 15; CT involvement categorized into < 10, 10–14, ≥ 15; Sputum TTP categorized into < 10, 10–14, 15–19, ≥ 20

PFT pulmonary function test, OR odds ratio, 95% CI 95% confidence interval, HbA1c hemoglobin A1c, CAT COPD assessment test, TTP time to positivity, CT computed tomography

^aAdjusted for age, gender, baseline CD4, smoking. Statistically significant associations are indicated in bold