Table 1.

Patient characteristics

Patient	Sex	Age	Sepsis etiology	SAPS II	SOFA	Norepinephrine HO µg/min/kg	Timing norepinephrine-esmolol introduction (hours)
1	F	82	Infectious pneumonia	79	12	2.00	8
2	H	58	Candidemia	61	14	0.57	9
3	H	54	Colo-pericardial fistulae	72	7	0.44	8
4	F	65	Infectious pneumonia	26	8	0.20	11
5	F	59	Ascitis	66	14	0.91	10
6	H	71	Soft skin	139	16	0.66	12
7	H	61	Infectious pneumonia	66	9	0,13	4
8	F	83	Biliary tract infection	73	14	0.83	5
9	F	24	Peritonitis	58	8	0.49	13

SAPS II Simplified Acute Physiology II Score, SOFA Sequential Organ Failure Assessment, HO O hours (baseline)