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. 2021 Jan 7;20:13. doi: 10.1186/s12933-020-01199-x

Table 3.

Clinical events

Parameter Placebo (N = 1206) Apabetalone (N = 1212) P value
First hospitalization for heart failure, n (%) 48 (4.0) 29 (2.4) 0.03
HR (95% CI) 0.59 (0.38–0.94)
Total hospitalizations for heart failure, n 70 35 0.01
HR (95% CI) 0.47 (0.27–0.83)
Cardiovascular death, n (%) 55 (4.6) 45 (3.7) 0.28
HR (95% CI) 0.81 (0.54–1.19)
First hospitalization for heart failure or cardiovascular death, n (%) 94 (7.8) 69 (5.7) 0.04
HR (95% CI) 0.72 (0.53–0.98)

Cardiovascular events in patients treated with apabetalone or placebo