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. 2020 Dec 14;21(2):139. doi: 10.3892/etm.2020.9571

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Copyright: © Xie et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of ADSCs on TGF-β1/Smad pathway in NFs, HSFs and KFs. A-C, Western blot was used to detect the expression of TGF-β1, Smad2, Smad3, p-Smad 2, p-Smad 3 and Smad 7 protein in (A) NFs (^***P<0.01 vs. NFs group), (B) HSFs (^***P<0.01 vs. HSFs group) and (C) KFs (^***P<0.01 vs. KFs group). ADSCs, adipose-derived mesenchymal stem cells; TGF-β1, transforming growth factor β1; Smad, mothers against decapentaplegic homolog; NFs, normal skin fibroblasts; HSFs, hypertrophic scar fibroblasts; KFs, keloid fibroblasts; p-, phosphorylated.; ns, not significant.