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. 2021 Jan 7;21:18. doi: 10.1186/s12877-020-01934-9

Table 2.

The results of univariate and multivariate Cox proportional hazard models

Factors Classification Nonfracture group
(n = 15,377)
Fracture group
(n = 2,097)
Crude HR (95% CI) P value Adjusted HR (95% CI) a
(n = 10,032)
P value
Age Continuous 1.04 (1.04–1.05)  < 0.001 1.04 (1.03–1.05)  < 0.001
Sex Men 7,550 786 Ref Ref
Women 7,827 1,311 1.59 (1.45–1.73)  < 0.001 1.85 (1.55–2.20)  < 0.001
PTSD symptoms No 10,451 1,237 Ref Ref
Yes 3,423 586 1.43 (1.30–1.58)  < 0.001 1.26 (1.10–1.44) 0.001
Experience of earthquake No 1,072 166 Ref Ref
Yes 14,305 1,931 0.82 (0.70–0.97) 0.017 0.92 (0.69–1.20) 0.531
History of mental illness No 14,170 1,896 Ref Ref
Yes 741 134 1.45 (1.21–1.72)  < 0.001 0.98 (0.76–1.27) 0.869
Need for assistance No 13,745 1,796 Ref Ref
Yes 1,249 240 1.85 (1.62–2.12)  < 0.001 1.14 (0.92–1.41) 0.240
History of cancer No 13,745 1,796 Ref Ref
Yes 1,249 240 1.31 (1.13–1.51)  < 0.001 1.49 (1.24–1.79)  < 0.001
History of stroke No 13,287 1,768 Ref Ref
Yes 1,434 254 1.41 (1.24–1.61)  < 0.001 1.25 (1.03–1.52) 0.023
History of heart disease No 12,068 1,545 Ref Ref
Yes 2,712 473 1.37 (1.23–1.51)  < 0.001 1.30 (1.13–1.50)  < 0.001
History of diabetes mellitus No 9,695 1,274 Ref Ref
Yes 4,942 734 1.14 (1.04–1.25) 0.004 1.23 (1.09–1.39)  < 0.001
Smoking habit Never smoked 8,866 1,321 Ref Ref (trend p = 0.057)
Former smoker 4,317 465 0.73 (0.66–0.81)  < 0.001 1.03 (0.86–1.24) 0.739
Current smoker 1,468 176 0.83 (0.71–0.97) 0.022 1.29 (1.02–1.63) 0.036
Drinking habit Never drinks or rarely drinks (less than once a month) 8,121 1,186 Ref Ref (trend p = 0.134)
Former drinker 847 111 0.95 (0.78–1.15) 0.595 1.22 (0.92–1.63) 0.171
Current drinker (more than once a month) 5,893 703 0.79 (0.72–0.87)  < 0.001 1.13 (0.98–1.31) 0.105
Level of sleep satisfaction Satisfied with sleep 4,738 571 Ref Ref (trend p = 0.142)
Slightly unsatisfied with sleep 4,488 634 1.15 (1.02–1.28) 0.018 1.04 (0.92–1.19) 0.552
Quite unsatisfied with sleep 1,408 242 1.40 (1.20–1.62)  < 0.001 1.03 (0.85–1.24) 0.796
Very dissatisfied with sleep or does not sleep at all 483 100 1.69 (1.37–2.09)  < 0.001 1.33 (1.02–1.74) 0.035
Exercise habit Almost daily 3,829 474 Ref Ref (trend p = 0.359)
2 to 4 times a week 4,620 611 1.06 (0.94–1.20) 0.338 1.00 (0.85–1.17) 0.976
Approximately once a week 2,193 312 1.16 (1.00–1.33) 0.047 1.08 (0.89–1.30) 0.443
Almost never 4,000 586 1.24 (1.10–1.40)  < 0.001 1.06 (0.90–1.25) 0.480

aAdjusted for age, sex, PCL score, experience of earthquake, history of mental illness, need for assistance, history of cancer, history of stroke, history of heart disease, history of diabetes mellitus, smoking habit, drinking habit, level of sleep satisfaction, and exercise habit. 95% CI 95% confidence interval, HR hazard ratio, Ref reference, PTSD post–traumatic stress disorder. Cox proportional hazard model; p < 0.05 was considered statistically significant